MyBioSource.com's NGAL (Capture Ab) is a Mouse monoclonal antibody. The NGAL (Capture Ab) Antibody was generated using LCN2, Lipocalin 2, NGAL, and Sip24 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, Western Blot, and Other.
Description
Lipocalin-2 (LCN2), also known as oncogene 24p3 or neutrophil gelatinase-associated lipocalin (NGAL), is a protein associated with neutrophil gelatinase. The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor